Searles struck eight fours in an enterprising 117 from 123 deliveries, as Comets made a challenging 246 for nine from their allocation of 50 overs at Wilson Road Recreation Ground.
Clarke Road romped home to victory, when they reached their target in 42.5 overs thanks to a match-winning hundred from the uncapped Mahadeo Moonasar, and snapped the two-match winning streak of their opponents.
Guyanese batsman Homchan Pooran scored 46 and former T&T Under-19 batsman Dion Bennett got 43.
T&T and West Indies batsman Lendl Simmions hit 94 from 118 balls to set up a 135-run victory for Merry Boys over Evergreen Sports at Fyzabad.
Simmons struck nine fours one six to make his presence felt in the local competition, following his return home with from Australia with West Indies last Thursday.
Merry Boys were dismissed for 258 in 47.5 overs, and Evergreen were bundled out for 125 in 27 overs with former national all-rounder Kenton Thompson taking four wickets for nine runs.
At Inshan Ali Park, West Indies Under-19 vice-captain Yannick Ottley collected four fours and one six in 83 from 107 balls to help Preysal end the unbeaten run of Central with a 90-run victory.
Preysal chalked up 232 for nine in 50 overs, and Central folded for 142 in 42 overs.
Uncapped Barbadian all-rounder Carlos Brathwaite also played a small part in Queen’s Park’s 84-run victory over Wanderers at Gilbert Park.
Brathwaite made 31 in Queen’s Park’s 255 for six before Wanderers were dismissed for 171.