The 25-year-old all-rounder uncorked a superb, unbeaten 167 for the Comets as they hammered the University of Trinidad and Tobago by 136 runs in the Carib T20 tournament at Pierre Road.
Khan blasted 15 fours and 12 sixes in his amazing knock which came off just 72 balls and which fired the Comets to an imposing 217 for two from their allotted 20 overs.
Khan was one of the standouts for T&T in the recent WICB first class season, scoring 221 runs and snaring 41 wickets with his right-arm leg spin.
In reply, UTT were bundled out for a mere 81 off 17 overs with T&T skipper Daren Ganga grabbing two wickets for eight runs.
In other matches, Guyanese Shemroy Barrington scored 70 to lead Evergreen to a 70-run victory over Valiants while T&T batsman Jason Mohammed scored an exciting 53-ball 93 to lead T&T Electricity Commission to victory over Wanderers.
At Brooklyn, the Guyanese trio of Mahendra Nagamootoo, Neil Williams and Royston Crandon all starred to spur as Moosai Sports to a 40-run win over Explorers.
Batting first, Moosai scored 157 all out with Crandon getting 21 and he then returned to grab two for 20 along with Williams (2-15) and Nagamootoo (2-20) to restrict their opponents to 117 for nine.